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What Causes Skin Cancer and How Can It Be Prevented?

  • Author by Raazi
  • Reviewed By Raazi
  • Last Edited : September 2, 2024
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Skin cancer is a disease that develops when malignant (cancer) cells proliferate within the skin’s tissues. Protecting the body is one of the skin’s most crucial roles. It covers the user against illness, potential damage, and sun rays. The skin controls the body’s internal temperature, and stores fluids, fats, and vitamin D.

The epidermis (the skin’s surface) and dermis (the skin’s main layer) are the two most noticeable of the many layers that make up the skin (lower or inner layer).

20% of people receive a skin cancer diagnosis. Sun-exposed skin is prone to developing skin cancer, often known as the uncontrolled growth of skin cells.

However, this typical cancer may also appear in less-frequently sun-exposed areas of the skin. If detected and treated promptly, most skin cancer cases are curable.

  • Skin cancer risk increases with the use of indoor tanning beds, especially in those under 35.
  • Frequent outdoor activities in childhood significantly raise the risk of skin cancer later in life.
  • Basal cell carcinoma is the most common but least deadly type of skin cancer.
  • Squamous cell carcinoma is more aggressive than basal cell carcinoma but less common.
  • Melanoma accounts for only 1% of skin cancer cases but is responsible for the majority of skin cancer deaths.
  • Merkel cell carcinoma is rare but can grow rapidly and is often fatal if not treated early.
  • Kaposi’s sarcoma can present as lesions that are mistaken for bruises or birthmarks.
  • Genetic mutations in the BRCA1 or BRCA2 genes can increase the risk of skin cancer.

Most Prevalent Forms of Skin Cancer

Melanoma, squamous cell carcinoma, and basal cell carcinoma are the three most common forms of skin cancer.

Sites on the Body Where Skin Cancer is More Common

Lips, ears, scalp, face, neck, chest, hands, arms, and legs are more at risk for developing skin cancer in women because of their greater exposure to the sun.

It may also show up in places seldom exposed to sunlight, such as the vaginal region, the hands, and the spaces between the toes and the fingers.

Cancer of the skin affects persons of all skin tones, especially those with darker complexions. People with darker skin tones are more likely to develop melanomas in parts of their bodies that are not often exposed to sunlight, such as the palms and soles.

Signs and Symptoms of Melanoma

You may get melanoma anywhere on your body. It may occur even on normal skin or in a pre-existing cancerous mole. The majority of male patients with melanoma have tumors on their faces or trunks.

The lower legs of females are a typical site for this kind of cancer to manifest. Both men and women are susceptible to developing melanoma on previously unexposed skin.

All skin tones are equally vulnerable to developing melanoma. People with darker skin tones are more likely to develop melanoma on their hands, soles, and beneath their fingernails and toenails.

Symptoms of melanoma include:

  • A massive brown area with darker spots. 
  • A small lesion with a ragged border that varies in color from red to pink to white to blue to blue-black
  • A mole that enlarges, changes in texture, or bleeds
  • A sore that causes discomfort by itching or burning
  • On palms, soles, fingers, or toes, or the oral, nasal, vaginal, or anogenital mucosa, it may appear as dark lesions

Cancer of the Basal Cell: Signs and Symptoms

Sun-exposed areas of the body, such as the neck or the face, have a higher incidence of basal cell carcinoma. Symptoms of basal cell carcinoma include: 

  • A lump that is waxy or pearly
  • A flat, flesh-coloured or brown lesion that scars over and then returns after healing 
  • A wound that bleeds or scabs over and then heals and reappears.

Squamous Cell Carcinoma: Signs and Symptoms

The most prevalent locations for squamous cell carcinoma to develop are the face, ears, and hands because of their exposure to the sun. Squamous cell carcinoma is more common in those with darker skin because it forms on less-frequently exposed areas of the body. Squamous cell carcinoma might seem as 

  • A solid red lump
  • A scaly, crusty lesion with a flat surface, like a bleeding or scabbing wound that heals

Less Frequent Signs and Symptoms of Skin Cancer

The following are examples of other less common forms of skin cancer:

Merkel cell carcinoma

Due to Merkel cell cancer, firm, shiny nodules form on or just below the epidermis and in hair follicles. Head and neck cancers and tumors in the trunk are the most prevalent sites for Merkel cell carcinoma.

Kaposi’s sarcoma

This is a rare cancer. It begins in the skin’s blood vessels and manifests as red or purple spots on the skin or mucous membranes.

People with weakened immune systems, such as AIDS or those using medicines that suppress the immune system, are more likely to develop Kaposi sarcoma. Those people who have had organ transplantation may also easily fall victim to it.

Sebaceous gland carcinoma

The skin’s oil glands are the origin of this uncommon and deadly cancer. Cancer of the sebaceous gland, which manifests as hard, painless nodules, may develop anywhere in the body.

However, in most cases, it occurs on the eyelid and is commonly misdiagnosed as caused by something else.

When Is the Time to See Your Doctor?

Try to visit your doctor soon if you notice any specific or even general changes to your skin. Not all alterations to the skin are because of skin cancer. Your doctor will investigate those alterations to your skin.

What Causes Skin Cancer?

Skin cancer can form when there are mal-metamorphosis or mutations in the DNA of skin cells. Due to the abnormalities, the cells multiply uncontrollably, becoming a tumor.

UV Radiation is One of the Several Possible Reasons

UV radiation, which is present in sunlight and tanning bed lights, is the primary culprit in skin cell DNA damage.

However, skin cancers that appear in areas of the body seldom exposed to sunlight cannot be attributed to sun exposure.

This shows that factors other than genetics may raise the risk of getting skin cancer, such as exposure to harmful chemicals or an impaired immune system.

Some Other Risk Factors of Skin Care

You may be more likely to get skin cancer if:

The color of your skin is fair

Individuals of all skin tones must take preventative measures against skin cancer. Though, less pigment (melanin) in your skin suggests less protection against the adverse effects of UV radiation.

Pale people, those who freckle easily, and those with light hair or eye color are at a greater risk of getting skin cancer than those of darker skin tones.

You have a horrible history of sunburns

One’s lifetime risk of developing malignant melanoma of the skin is raised if one had only a blistering sunburn in childhood or as a teenager. Sunburns in adults also increase the danger.

You spend too much time in the sun

Anyone who spends much time outside should use sunscreen and protective gear since prolonged sun exposure increases the chance of developing skin cancer. Tanning, which includes the use of tanning lights and beds, is also dangerous.

A tan develops when your skin reacts negatively to excessive levels of UV radiation.

You live in sunny or mountainous regions

The sun’s rays reach with more severity to people who live in warmer climates than those who inhabit more excellent areas. Living at a higher altitude, where the sun is brightest, increases your risk of radiation exposure.

You have moles on the face

Individuals with a high number of moles or atypical moles (dysplastic nevi) are at an increased risk for developing malignant melanoma. These moles are more prone to become cancerous than usual because of their abnormal appearance and size.

If you or a family member have a history of mole abnormalities, be on the lookout for any changes.

You have precancerous skin lesions

The chance of developing skin cancer is raised by actinic keratoses, a kind of precancerous skin disease. It is common for these precancerous skin growths to manifest as rough, scaly brown to dark pink areas. Fair-skinned people who have spent a lot of time in the sun get them on their scalps, faces, and hands.

You have a family history of skin cancer

The likelihood of developing skin cancer is enhanced if a parent or sibling has already been diagnosed with the disease.

Have you ever had some other type of cancer

 You are more likely to have another kind of skin cancer if you’ve already had one. Mutations in the BRCA1 or BRCA2 genes cause skin cancer in humans, and once even it is cured, can recur in some other form. 

You have a compromised immune system

Skin cancer is more common in those with compromised immune systems. People who have had organ transplants and are on immunosuppressant medicines fall into this category.

You already have some radiation as therapy

An increased incidence of skin malignancies, especially basal cell carcinoma, has been linked to the use of previous radiation treatments. Usually, they are used to treating benign skin conditions, including eczema and acne.

You inhale some chemicals or remain in contact with them

One’s chance of acquiring skin cancer may rise if exposed to chemicals like arsenic.

How to Prevent Skin Cancer?

The majority of cases of skin cancer may be avoided. You protect yourself and be sure to follow these skin cancer prevention tips:

Avoid sunlight whenever possible

During the day, shade is preferable to direct sunshine. There is a common misconception that the sun’s rays are at their strongest between 10am and 4pm.

Outside activities should be scheduled for other times of the day, no matter how cold or cloudy the sky is.

Dangerous ultraviolet radiation (UVR) strikes at any time of year, and clouds provide little shelter from it. If you stay indoors during the sun’s hottest parts of the day, you won’t have to worry about becoming burnt or tanned, which may damage your skin and raise your risk of developing skin cancer.

Prolonged exposure to the sun has been linked to an increased risk of developing skin cancer.

Use sunscreen year-round

Sunscreens do not entirely protect against melanoma-causing ultraviolet (UV) radiation.

On the other hand, they serve a crucial function in the overall system of sun protection. Applying broad-spectrum sunscreen with at least an SPF of 30 is recommended even on overcast days. 

Spread sunscreen all over your skin and reapply it every two hours. Be sure to do this more often if you plan on engaging in strenuous physical activity like swimming or heavy perspiration.

The backs of your hands, neck, and lips are all areas that might benefit from a generous sunscreen application. Your ears and lips are not immune to sun damage.

Wear proper protective gear

Sunscreens do not provide foolproof protection from the sun’s harmful UV radiation. Therefore, it’s essential to cover up as much of your skin as possible by dressing in heavy, tightly woven clothing. More than a baseball cap or visor, a broad-brimmed hat keeps the sun off your face and neck.

Another vendor of sun-protective apparel is out there. Consult a dermatologist for advice on suitable products. Keep your shades with you. There are two forms of ultraviolet radiation, UVA and UVB. Therefore, it’s important to choose sunglasses that protect against both.

Tan in the sun, not the tanning bed

The use of tanning beds, which include lamps that generate UV radiation, has been linked to an increased risk of developing skin cancer. So avoid using them.

Thoroughly examine your skin regularly

 Use mirrors to do a thorough examination of your whole body, paying close attention to your face, neck, ears, and scalp.

Check the insides and outsides of your arms and hands and the tops of your shoulders and upper back. Pay close attention to the soles of your feet and the spaces between your toes as you inspect the front and back of both legs. Check both your genital region and the area between your thighs.

Getting as little sun as possible is one of the best ways to protect yourself against skin cancer. If you want to catch skin cancer in its early stages, you must check your skin often for any changes that could cause concern

Be cautious of sun-sensitizing antibiotics and medications

Some medications may increase your sensitivity to sunlight, so exhibit thoughtfulness outside. Your skin may become more sensitive to the sun if you use antibiotics or other drugs readily available both by prescription and over the counter.

See your doctor or pharmacist to learn more about the potential adverse effects of the medicines you are currently taking.

Because of the increased risk of sunburn, it is essential to avoid prolonged exposure to sunlight if these medications are causing you to be photosensitive.

Be aware of any changes to your skin

Be mindful of any changes to your skin and let your doctor know. It’s essential to keep an eye out for new skin growths and any changes to existing freckles, moles, lumps, or birthmarks.

Skin Cancer Treatment Options

Some of the primary skin cancer therapies are:

  • Surgery
  • Radiation therapy
  • Photodynamic Therapy Included in Chemotherapy
  • Immunotherapy 
  • Radiology interventional
  • Chemical peeling
  • Clinical trials may also result in something new

Takeaway

If you have skin cancer, your dermatologists use skin examination tests and methods to diagnose the disease. A thorough analysis of the patient’s medical history and physical examination is done to seek any anomalies that might suggest sickness.

The patient’s medical background, including any illnesses they may have had and treatments, are also given deep consideration.

Dermatologists use different practices to diagnose the malignancy. A “skin exam” is a visual inspection of the skin to look for lumps, or a skin biopsy is done.

In a biopsy, a pathologist takes a sample of the patient’s skin containing the suspicious development and studies it under a microscope. 

Numerous factors affect the prognosis (the probability of recovery) and the treatments offered.

Early skin cancer detection gives patients the best chance of positively responding to therapy.

What Causes Skin Cancer and How Can It Be Prevented?

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